What causes SIDS or sudden infant death syndrome?
No single cause of SIDS has been found. It's believed to result from a combination of a baby's underlying vulnerability, a critical stage of development (usually 2-4 months), and an outside stressor like unsafe sleep conditions.
Known risk factors include tummy or side sleeping, soft bedding, overheating, smoke exposure, prematurity, and bed-sharing, while back sleeping, room-sharing, and breastfeeding lower risk.
Good
Based on national guideline statements plus large case-control and cohort studies; because SIDS deaths can't be studied with randomized trials, the evidence is mainly observational rather than experimental.
What the evidence says
The honest answer is that no one knows exactly what causes SIDS. By definition, it's diagnosed only after doctors rule out every other explanation for a baby's sudden death during sleep.
Most experts now think SIDS happens through a 'triple risk' combination: a baby who has some hidden vulnerability (such as differences in brain areas that control breathing or waking up), during a sensitive age window (most deaths happen between 2 and 4 months), plus an outside stress like tummy sleeping, overheating, or secondhand smoke that tips things over the edge.
Known risk factors include sleeping on the stomach or side, soft bedding or soft sleep surfaces, bed-sharing, overheating, prematurity or low birth weight, and smoking or substance use during or after pregnancy. Protective steps include placing babies on their backs for every sleep, room-sharing without bed-sharing for the first six months, breastfeeding, and keeping the home smoke-free.
One reassuring fact: large safety reviews have found no link between childhood vaccines and SIDS, even though the peak vaccination age overlaps with the peak SIDS age.
Sources
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Guideline
Sudden Infant Death Syndrome
Canada.ca (Public Health Agency of Canada), 2024
Canadian federal guidance: cause unknown, lists risk-reduction steps.
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Guideline
Safe sleep for babies
Canadian Paediatric Society, Caring for Kids, 2024
Canadian pediatric guidance on SIDS risk and protective factors.
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Guideline
Sleep-Related Infant Deaths: Updated 2022 Recommendations
American Academy of Pediatrics, Pediatrics, 2022
Describes the triple-risk model and full risk factor list.
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Guideline
About SUID and SIDS
CDC, 2025
US federal overview of SUID/SIDS definitions and data.
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Guideline
Sudden Infant Death Syndrome (SIDS) and Vaccines
CDC Vaccine Safety, 2024
Confirms no link found between vaccines and SIDS.
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Systematic review
Sudden Infant Death Syndrome (StatPearls review)
NCBI Bookshelf, 2026
Evidence review summarizing SIDS risk factors and definitions.
✓Reviewed by CH, MD, FRCPC
Reviewed by a specialist physician certified by the Royal College of Physicians and Surgeons of Canada, who has read this answer against the sources listed above and confirmed it reflects them. That is not medical advice about your child. How we review
Answer checked July 29, 2026